Dissolution Tester DS 14000+ with Syringe Pump

Tablet Dissolution Tester

The tablet dissolution testing apparatus DS 14000 with syringe pump offers advanced features as a complete dissolution offline sampling system which consists of 12 port Multi syringe pump system with proprietary high efficiency & maintenance free stepper motor drive enables testing for long duration.

In this dissolution testing apparatus 15 methods with parameters can be stored and dissolution  can be started with the last run parameters. The configuration allows two different runs to be performed at the same time with identical conditions. In case of power failure the dissolution testing system restarts the run where it had left off.

Labindia Dissolution Testing system DS 14000 with syringe pump is 100% USP, BP, EP, IP compliant and fulfils the specifications in accordance to the FDA mechanical calibration.

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Tablet Dissolution Testing Apparatus DS 14000 with Syringe Pump
Standard Features of Dissolution Tester DS 14000+ with Syringe Pump
  • User-friendly, complies with current USP, IP, BP, & EP and ASTM specifications.
  • Alphanumeric polyester soft keys for keyboard.
  • External vibration free Water Circulator for uniform water circulation with audible and low water level alarm.
  • Mono shaft design with automatic adjustment for 25 mm depth setting with easy changeover between Apparatus I & II eliminates routine height validation as per USP.
  • Paddles, Baskets and Vessels are laser marked with serial numbers for traceability.
  • Tablet dispenser drops 12 dosage form at single instance.
  • Facility to monitor Vessel temp, with DTS Technology (Digital Temperature Sensor)
  • Easy placement and locking of vessels, the Ease-align system allows the vessels to simply slide into the place (Bionet Locking)
Intelligent Sampling System
  • Automated sampling as per USP Specifications. Sampling tubes are lowered in the media only at the time of sampling and withdrawn immediately after sampling, thus no par t of the assembly contributes motion, agitation or vibration (500, 750, 900 & 1000 ml).
  • Sampling tubes are accurately moved to the USP sampling position i.e. a zone mid way between the sur face of media and the top of paddle/basket parameters, not less than 1 cm from the vessels wall as selected in the method.
  • 12 bowls temperature monitoring system automatically measures and records the temperature of individual vessel at specified sample points.
Sample Collection
  • 12 X 6 X 2 sets of samples can be collected. For more sampling interval, 24 X 6 collection trays are available.
  • Option of 1.5ml & 2ml HPLC vials is available.
  • Over Head Design for electronic safety and fail safe operation.
  • Sensor to locate proper position of tray with alar m facility for collection of sample.
  • Wide mouth vial to minimise SLS spillover problem due to foaming Characteristics.
Syringe Pump
  • Multi-Syringe Pump system designed for automatic Sample Collection from Dissolution Bowls of Labindia Dissolution Test Apparatus DS 14000+.
  • Perform Rinsing the sample tubing path, Replenishing the blank media volume to bowls and Sample Dilution tasks (Optional for future development).
  • Controlled through Labindia dissolution Instr ument Controller with Operation Status Indications on the front panel for user information.
  • Inert fluid path consisting of Teflon carrier tubing, Gastight Glass Syringes with Teflon Plunger and PEEK body Valves.
  • Proprietary high-efficiency and maintenance-free Stepper motor drive system.
  • Long-life 4 port Rotary shear valves with SS Body.
  • Volume accuracy better than ±2%.
Regulatory Compliance
  • DS 14000+ with Syringe Pump meets all requirements relating to validation, qualification and calibration.
  • Appropriate qualification documents (I.Q. / O.Q.) can be supplied with the instrument.
Typical Specification
Parameters
DS14000 with Piston Pump
DS14000 with Syringe Pump
Dissolution Vessel

Option for Polycarbonate / Glass Vessels (clear, amber, peak vessels, 250, 150 & 100 ml dissolution vessels available). 

Display

40*2 LCD Display (Alphanumeric)

RPM

20 to 250 RPM

RPM Accuracy

± 1 RPM

Temprature Range

20° to 55° degree

Temp Accuracy

± 0.1° C

Method

15

User 

10

Role

2 Role(Admin & User)

Connectivity

RS-232

Test Report

Last Report

21 CFR Compliance

Yes( EDC Software)

Auditrail

NA

E Signature

NA

Sampling Interval

30

Sample Interval Time

1min to 720 hrs

Pump Used for Sample Collection

Piston Pump

Syringe Pump

Sample Volume Range

0.5ml - 25ml

0.5ml-10ml

Rinsing

Rinse

Cleaning Cycle

Yes

Sample Collector Type

Open

HPLC Vials Tray

Yes

Option for 1.5ml & 2ml HPLC Vials

Auto Tablet Dispenser

Manual

Tray detection & identification

NA

Contact parts

All Contacts Parts are inert

Sample Collection

12*6*2 Sample Collection Tray Tray.(24*6 Optional)

12*6*2 & 24*6

Automatic Vessel Centering

Yes (Complies as per US FDA division of
pharmaceutical analysis (Ref. Document no.
DPA-LOP.002)

Center Shaft

± 0.5mm

Lift Mechanism

Motorized (Automatic) for accurate height

Heater

Isolated temperature controller (vibration-free & precise) with wake up & sleep modes (saves time & energy) (1KW)

Shaft

MonoShaft - Easy Switch Over between Paddle & Basket

Height Adjustment

Automatic height adjustment

Apparatus

Unique design of USP apparatus
I, II, V, VI & intrinsic dissolution can be used. Also Small Volume Dissolution kit 250ml & 150ml can be used.

Laser Marking on Accessories

Yes

Water Bath

Clear acrylic molded water Bath 

Water Level Sensor

Yes

Power Failure

Yes


LABINDIA reserve the right to change specification without notice as part of its continuous product development.

Software
  • Alphanumeric entries of Sample Name, Sample Number and Identification Number for authentication.
  • Built-in Real Time Clock (RTC) for date and time on display and on printout.
  • Daily Auto Incremented Run Number and factory entered CUSTOMER NAME with Instrument Serial Number on report printouts
  • Non-Volatile memory storage of 15 methods with parameters.
  • Two tier password protection of Admin and User
  • Reports can be obtained even after Resetting / Power off / Power failure conditions.
  • Error indication helps user to trace the problem.
  • Audible indication for ready state of instrument.
  • Validation Software to validate RPM, Temperature, sampling volume & replenish volume.
Tablet Dissolution Testers